Plexr Plus
THE GOLD STANDARD IN PLASMA TECHNOLOGY
THE PLASMA EXERESIS WITH PLEXR®
Plasma Exeresis technology has been conceived and developed by GMV, a company with over 10-year experience in plasma technology and holding the Plexr® trademark (Plexr Plus), the first plasma device in medical aesthetics all over the world, internationally patented.
The applications of Plexr® involve many medical disciplines as dermatology, aesthetic medicine, oculoplastic surgery, dentistry, gynaecology.
The methodology/technique of use is constantly assisted by scientific research and clinical studies, in ltaly and Worldwide, collaborating with top KOLs and prestigious Universities.
PLASMA
A term derived from the Greek for ‘entity’ or ‘form’, is the fourth state of matter and it is constituted by negatively charged electrons and positively charged ions with an overall neutral net charge. It can be created when a difference in voltage matches the dielectric breakdown of the gas included into the field.
Atoms are the elements of molecules; when the interaction among molecules is high, they result in a solid, able to maintain shape a volume until an extremely high strength can break such interaction. When the interaction is weak among molecules, this can result respectively in a liquid, maintaining volume but losing shape, or in a gas, which maintains no shape or volume, but occupies all the available space.
When an external energy can split the molecules of the gas in positive and negative parts, we reached the fourth state of the matter: plasma. When activated, Plexr ionizes the air between the tip of the device and the human body by generating an appropriate potential difference.
The electric breakdown of the air is around 3000 V per mm, depending from some factors such as humidity and bodies the physical phenomenon is generated by. Using the Plexr® signal parameters, around half millimetre is the needed distance for the ionization of the air atoms.
No plasma is generated when the probe is in direct contact with the tissue or too distant from it.
The plasma generation is similar to a micro lightning bolt that acts directly only on the epidermis. Before sublimating, the corneocytes transmit a selective estimated quantity of energy that reaches the right deepness of dermis, without irradiation (laser/light) or electric shock (radioscalpel/current).
No any form of energy is delivered directly from the device to the deeper tissue, no eddy currents are generated.
The action of Plexr Plus on tissues allows:
1- immediate contraction of the collagen fibers
2- collagen reorganization
3- formation of new collagen (type III)
4- renewal the epidermal tissue.
This mechanism has been proved through several scientific studies (see literature section).
Technology and Applications
Plexr Plus is conceived with three different handpieces: the output of each handpiece is in fact optimized so that an ad-hoc signal can be performed in function of the specific treatment. The choice of the handpiece is strictly dependent by the treatment the Dr. is going to perform.
WHITE HANDPIECE Blepharoplasty, lentigo solaris, moderate active acne, small wrinkles, umbilical lifting, small benign skin neoformations, coadjuvant for small keloids, moderate cutaneous renewal and skin rejuvenation, vaginal rejuvenation and vulvoplasty.
GREEN HANDPIECE Active acne, medium benign skin neoformations, seborrheic keratosis, elastosis, dyschromia, small ruby angiomas, face lifting, xantelasmas, small fibromas, small scars.
RED HANDPIECE Voluminous benign skin neoformations, big
fibromas coadjuvant for keloids, big ruby angiomas, deep scars, acne scars, resurfacing, warts, seborrheic warts, hyperkeratosis, gingival whitening and so on.
However, there are factors that can furtherly influence the handpiece choice:
– Experience of the doctor: as initial approach it is suggested to use the white handpiece, in order to better achieve and understand functionality of the device. With constant attendance to training courses and acquisitions of experience you will gather the necessary skills to treat different types of skin pathologies.
– Entity of the skin pathology.
– Skin type of the patient.
GMV strongly recommends to use only official Plexr Tips.
These kinds of needles, made with medical-grade stainless steel, are conceived to work combined with Plexr’s handpieces: they have been studied and designed to generate the correct quantity of Plasma.
The Plexr Tips are single use to optimize the result
Why Plexr Plus is different from other Plasma devices
Plexr is the unique device able to recreate the precise and stable phenomenon of Plasma intended for medical use, allowing the Doctor to work safely and successfully.
Plexr is designed to reproduce correctly the necessary physical dimensions observed in several scientific studies (see literature). Producing a general and incorrect signal to generate plasma is definitely not sufficient and/or dangerous.
To do that, specific parameters and specific electronic design are mandatory. This property avoids deep thermic damage, electric shock and allows to reach the desired result with minimal downtime.
The focused micro-plasma beam due to the ionization of the gases contained in the air, sublimates the stratum corneum of the epidermal tissue where the spot is performed, but the ionic flow doesn’t spread out to deeper tissue. The basal lamina is preserved and there is no dermal or electrical damage (see literature).
A device designed with different parameters and composed by different electrical components causes different or even unpredictable/dangerous effects:
– Lower working frequency: too high penetration, thermic damage, high skin-tip distance (less accuracy).
– Higher working frequency (electrosurgical unit): reduced skin-tip distance, current flow, high superficial energy (skin cut).
– Higher working voltage: too high penetration, thermic damage, high skin-tip distance (less accuracy).
– Lower working voltage: no effect.
Therefore, possible consequences in using different devices are:
• more pain for the patient
• no same results
• scarring
• expertise of the operator: the space between good result and side effect (scars) is minimal. Trying to get better results means to risk scarring. Plexr does not produce scarring at all.
• Not estimable or long-lasting prominent side effects: redness (erythema), oedema and Post Inflammatory Hyperpigmentation (PIH).
• The stable plasma generated by Plexr opens to other protocol.
Why Plexr is different from LASERs
The target tissue of the coherent, monochromatic and unidirectional radiation turns out a new heat source, increasing temperature in the surrounding tissue.
Furthermore, LASER:
• Is skin colour and pathology depending
• Produces a not uniform effect
• Is more expensive
• Causes a longer downtime
• Implies more difficult treatment
• Is less versatile -cumbersome, no wireless, no portable
Why Plexr is different from electrosurgical units (radiofrequency)
Electrosurgical units / Radio scalpel delivers currents with higher intensity (X10) and frequency. This makes the device more aggressive to the skin.
• Return electrode pad (current diffused all over the body)
• Uncontrolled current flow
• More invasiveness (Cut)
• Diffused thermic damage
• Less versatility (no wireless, no portable)
• Not uniform effect
• Longer downtime
The upgrade many people were looking for
-Microprocessor checking online the output signal -assuring the output is respecting the scientific literature parameters-
– Patented design by GMV
– Touch screen display
– Video tutorials
– Extractable lithium polymers battery pack (12h recharge)
– Software updates for new functions –fractional mode-
– High quality packaging
– The handpieces ion lithium battery (5h high performance)
– Portable charging-base for car lighter and power plug
– Quality of the components
Plexr® & GMV Certificates
Plexr, like all GMV medical devices, has been approved by the European Community and from notified bodies and government entities around the world.
List of most important international certificates:
- ISO 9001
- IQNET: International certification network
- ISO 13485
- EC CERTIFICATE: Full Quality Assurance System Approval Certificate
ALWAYS WITH YOU
Made in Italy
- Immediate technical support
- Responsive communication with our staff
- Online and on-site support
Choose the safety for your body.
Choose the best efficacy treatments.
Choose Plexr Plus: The Original One
References
Scientific research proves the effectiveness and safety of Plexr. Doctors and researchers from all over the world have made studies using Plexr, and they published their results on different journals. Most of these journals also have the Impact Factor index, which is one of the most widely used research assessment indexes recognized at international level.
GMV – Advanced technologies for Medical Aesthetics
List of most important and recent publications:
– Tsioumas G. Sotiris, et al. A descriptive Study on the Applications of Plasma Exeresis in Dermatology. Journal of Clinical and Aesthtetic Dermatology. 2021- Nejat F, et al. The assessment of the concentration of candidate cytokines in response to conjunctival-exposure of atmospheric low-temperature plasma in an animal model. BMC Ophthalmol. 2021
